I Am Seeking a Clinical Trial

The treatment of brain tumors has been a clinical challenge, with many anticancer drugs unable to penetrate tumor tissue, and tumors eventually becoming resistant to those that do. For many patients with brain and spine tumors, the greatest hope for effective treatment lies in clinical trials. Our patients have access to clinical trials of innovative investigational therapies. For more than a decade, researchers in the Brain Tumor Center have directed clinical trials evaluating cancer vaccines designed to stimulate the immune system to attack brain tumor cells. Examples of these treatments include:

• ICT-107, a novel immunotherapy developed for patients with glioblastoma. Our center enrolled more patients in this study than any other center.
• Toca 511 and Toca FC immunotherapies for patients with recurrent high-grade glioma. Our center was also among the highest enrollers.
• Interleukin-12-based immunotherapy for recurrent glioblastoma.

Our investigators participate in pharmaceutical-sponsored and investigator-initiated clinical trials as well as Radiation Therapy Oncology Group (RTOG) clinical trials and Cancer Institute of New Jersey Oncology Group (CINJOG) studies. Both RTOG and CINJOG are leading multicenter research organizations systematically assessing novel treatment approaches against cancer.

Your treatment team will let you know if you are eligible for a clinical trial. Your decision to participate is voluntary.