Objective and Integrated Core Approach

The goal of MAVDA is to identify promising Lead compounds for the treatment of viruses with pandemic potential and advance them through the development matrix as Preclinical Development Candidates (PDC) suitable for downstream preclinical investigational new drug (IND) development.

Viruses and Targets

Antivirals targeting specific viral families with high potential to cause a pandemic in the future. These include paramyxoviruses, bunyaviruses, togaviruses, filoviruses, picornaviruses and flaviviruses (including the viruses that cause yellow fever, dengue and Zika).

Developmental Research Projects

DRPs are intended to expand the scope and range of current research and investigators involved in antiviral discovery, allowing for testing of novel ideas (with limited preliminary data) and development of new technologies. 2023 application period closed. Next cycle starts December 2024.

Mentored Research Projects

MRPs are intended to increase the availability of qualified researchers and other personnel for antiviral discovery research by providing opportunities to further their professional advancement. MRPs must relate to the Center objectives and may be used to support post-doctoral fellows, early career investigators, or senior investigators new to the field of antiviral discovery and development. 2023 application period is closed. Next cycle starts December 2024.